Course readings.

SES #	TOPICS	READINGS
2	EBV and lymphoproliferative disorders	Paper 1 Epstein, M. A., B. G. Achong, and Y. M. Barr. "Virus Particles in Cultured Lymphoblasts from Burkitt's Lymphoma." The Lancet 1 (1964): 702-703. Paper 2 Deacon, E. M., G. Pallesen, G. Niedobitek, J. Crocker, L. Brooks, A. B. Rickinson, and L. S. Young. "Epstein-Barr Virus and Hodgkin's Disease: Transcriptional Analysis of Virus Latency in the Malignant Cells." J Exp Med 177 (1993): 339-349.
3	MHV-68 as a model in mice for gamma herpes viruses	Steed, A. L., E. S. Barton, S. A. Tibbetts, D. L. Popkin, M. L. Lutzke, R. Rochford, and H. W. Virgin IV. "Gamma Interferon Blocks Gammaherpesvirus Reactivation from Latency." J Virol 80 (2006): 192-200.
4	Gastric cancer and Helicobacter pylori I	Paper 1 Marshall, B. J., and J. R. Warren. "Unidentified Curved Bacilli in the Stomach of Patients with Gastritis and Peptic Ulceration." The Lancet 323 (1984): 1311-1315. Paper 2 Tsuda, M., M. Karita, M. G. Morshed, K. Okita, and T. Nakazawa. "A Urease-negative Mutant of Helicobacter Pylori Constructed by Allelic Exchange Mutagenesis Lacks the Ability to Colonize the Nude Mouse Stomach." Infection and Immunity 62 (1994): 3586-3589.
5	Gastric cancer and Helicobacter pylori II	Paper 1 Bagnoli, F., L. Buti, L. Tompkins, A. Covacci, and M. R. Amieva. "Helicobacter Pylori CagA Induces a Transition from Polarized to Invasive Phenotypes in MDCK Cells." Proc Nat Acad Sci 102 (2005): 16339-16344. Paper 2 Houghton, J., C. Stoicov, S. Nomura, A. B. Rogers, J. Carlson, H. Li, X. Cai, J. G. Fox, J. R. Goldenring, and T. C. Wang. "Gastric Cancer Originating from Bone Marrow-derived Cells." Science 306 (2004): 1568-1571.
6	Human papillomavirus and cervical cancer I	Paper 1 Boshart, M., L. Gissmann, H. Ikenberg, A. Kleinheinz, W. Scheurlen, and H. zur Hausen. "A New Type of Papillomavirus DNA, its Presence in Genital Cancer Biopsies and in Cell Lines Derived from Cervical Cancer." EMBO Journal 3 (1984): 1151-1157. Paper 2 Talis, A. L., J. M. Huibregtse, and P. M. Howley. "The Role of E6AP in the Regulation of p53 Protein Levels in Human Papillomavirus (HPV)-positive and HPV-negative Cells." J Biol Chem 273 (1998): 6439-6445.
7	Human papillomavirus and cervical cancer II	Paper 1 Dillner, J., L. Dillner, J. Robb, J. Willems, I. Jones, W. Lancaster, R. Smith, and R. Lerner. "A Synthetic Peptide Defines a Serologic IgA Response to a Human Papillomavirus-encoded Nuclear Antigen Expressed in Virus-carrying Cervical Neoplasia." Proc Nat Acad Sci 86 (1989): 3838-3841. Paper 2 Kirnbauer, R., F. Booy, N. Cheng, D. R. Lowy, and J. T. Schiller. "Papillomavirus L1 Major Capsid Protein Self-assembles into Virus-like Particles that are Highly Immunogenic." Proc Nat Acad Sci 89 (1992): 12180-12184.
9	Hepatitis C, liver cirrhosis and hepatocellular carcinoma	Paper 1 Pileri, P., Y. Uematsu, S. Campagnoli, G. Galli, F. Falugi, R. Petracca, A. J. Weiner, M. Houghton, D. Rosa, G. Grandi, and S. Abrignani. "Binding of Hepatitis C Virus to CD81." Science 282 (1998): 938-941. Paper 2 Lindenbach, B. D., M. J. Evans, A. J. Syder, B. Wölk, T. L. Tellinghuisen, C. C. Liu, T. Maruyama, R. O. Hynes, D. R. Burton, J. A. McKeating, and C. M. Rice. "Complete Replication of Hepatitis C Virus in Cell Culture." Science 309 (2005): 623-626.
10	Atherosclerosis as an inflammatory disease I	Paper 1 Speir, E., R. Modali, E. S. Huang, M. B. Leon, F. Shawl, T. Finkel, and S. E. Epstein. "Potential Role of Human Cytomegalovirus and p53 Interaction in Coronary Restenosis." Science 265 (1994): 391-4. Paper 2 Streblow, D. N., C. Soderberg-Naucler, J. Vieira, P. Smith, E. Wakabayashi, F. Ruchti, K. Mattison, Y. Altschuler, and J. A. Nelson. "The Human Cytomegalovirus Chemokine Receptor US28 Mediates Vascular Smooth Muscle Cell Migration." Cell 99 (November 1999): 511-20.
11	Atherosclerosis as an inflammatory disease II	Paper 1 Burnett, M. S., S. Durrani, E. Stabile, M. Saji, C. W. Lee, T. D. Kinnaird, E. P. Hoffman, and S. E. Epstein. "Murine Cytomegalovirus Infection Increases Aortic Expression of Proatherosclerotic Genes." Circulation 109 (2004): 893-7. Paper 2 Vliegen, I., S. B. Hemgreen, G. E. Grauls, C. A. Bruggeman, and F. R. Stassen. "Mouse Cytomegalovirus Antigenic Immune Stimulation is Sufficient to Aggravate Atherosclerosis in Hypercholesterolemic Mice." Atherosclerosis 181 (2005): 39-44.
12	Diabetes and multiple sclerosis as an inflammatory disease	Paper 1 Dotta, F., S. Censini, A. G. van Halteren, L. Marselli, M. Masini, S. Dionisi, F. Mosca, U. Boggi, A. O. Muda, S. D. Prato, J. F. Elliott, A. Covacci, R. Rappuoli, B. O. Roep, and P. Marchetti. "Coxsackie B4 Virus Infection of Beta Cells and Natural Killer Cells Insulitis in Recent-onset Type 1 Diabetic Patients." Proc Nat Acad Sci 104 (2007): 5115-20. Paper 2 Wucherpfennig, K. W., and J. L. Strominger. "Molecular Mimicry in T Cell-mediated Autoimmunity: Viral Peptides Activate Human T Cell Clones Specific for Myelin Basic Protein." Cell 80 (1995): 695-705.