Readings

Assigned readings are from the course text:

Buy at Amazon Watson, James D., Tania A. Baker, Stephen P. Bell, Alexander Gann, Michael Levine, Richard Losick. Molecular Biology of the Gene. 5th ed. San Francisco, CA: Pearson/Benjamin Cummings, 2003. ISBN: 9780805346350 .

Lec # Topics Readings
1 Replication (Replication Enzymes) Watson, pp. 181-194.
2 Replication (Replication Fork) Watson, pp. 195-212.
3 Replication (Prok. System) Watson, pp. 212-221.
4 Replication (Euk. Systems) Watson, pp. 212-221.
5 Chromatin Assembly Watson, pp. 151-165 and 222-233.
6 DNA Mismatch Repair Watson, chapter 9.
7 DNA Repair II Watson, chapter 9, pp. 246-257.
8 DS Break Repair

Homologous Recombination
Watson, chapter 10, pp. 259-268.
9 Homologous Recombination Enzymes Watson, chapter 10.
10 Meiotic Recombination Watson, chapter 10.
11 Site-specific Recombination Watson, chapter 10, pp. 293-310.
12 Transposition  
13 Transcription: Prok. Machinery and Promoters  
14 Transcription: Euk. Machinery and Promoters Watson, chapter 12, pp. 347-363.
15 Transcription: Regulation I Watson, chapter 16, pp. 483-504.
16 Transcription: Regulation II Watson, chapter 12 and 17, pp. 363-377 and 529-551.
17 RNA Processing I Watson, chapter 12 and 17, pp. 363-377 and 529-551.
18 RNA processing II Watson, chapter 13.
19 RNA Processing: Regulation Watson, chapter 13.
20 RNA Editing

RNAi and miRNAs
Watson, chapter 13, pp. 563-565.
21 Translation: Basic Machinery I Watson, chapter 14, 16 and 17, pp. 411-454, 504-511 and 565-567.
22 Translation: Basic Machinery II Watson, chapter 14, 16 and 17, pp. 411-454, 504-511 and 565-567.
23 Translation: Regulation I Watson, chapter 14, 16 and 17, pp. 411-454, 504-511 and 565-567.