Notes from lectures 3 through 25 are courtesy of Laura Proctor. Used with permission.
LEC # | TOPICS | |
---|---|---|
Protein Modeling | ||
1 | Introduction and Protein Modeling Questions (PDF) | |
2 | Models of Proteins (PDF) | |
3 | Discrete Conformational Search (PDF) | |
4 | Binding and Docking (PDF) | |
5 | Molecular Dynamics Simulation (PDF) | |
6 | Molecular Dynamics and Electrostatics (PDF) | |
7 | Continuum Electrostatic Modeling I (PDF) | |
8 | Continuum Electrostatic Modeling II (PDF) | |
9 | Electrostatic Optimization and Design (PDF) | |
10 | Electrostatics Modeling (PDF 1) (PDF 2) | |
11 | Statistical Mechanics (PDF) | |
Network Modeling | ||
12 | Statistical Mechanics (cont.) (PDF) | |
13 | Formulating and Simulating Network Models in Biology (PDF) | |
14 | Formulating Models (PDF) | |
15 | Nonlinear Dynamics and Stability (PDF) | |
16 | Steady-State Problems (PDF) | |
17 | Parameter Fitting and Estimation (PDF) | |
18 | Parameter Estimation; Robustness, Fragility, Control (PDF) | |
Image Modeling | ||
19 | 2-D and 3-D Light Microscopy; Image Reconstruction (PDF) | |
20 | Deconvolution (PDF) | |
21 | Deconvolution II (PDF) | |
22 | Blind Deconvolution (PDF) | |
23 | Optical Flow (PDF) | |
24 | High-Throughput Data and its Analysis (PDF) | |
25 | Inference and Statistics (PDF) | |
26 | Roundup |
Supplemental Notes
Adjoint Sensitivity Analysis for Optimization (PDF) (Courtesy of Joshua Apgar and Jared Toettcher. Used with permission.)