Instructor(s)
Prof. Peter Dedon
Prof. Steven Tannenbaum
Dr. Mark Murcko
Dr. Charles Knutson
MIT Course Number
20.201
As Taught In
Fall 2013
Level
Graduate
Course Description
Course Features
- Lecture notes
- Projects and examples
- Assignments: problem sets with solutions
- Assignments: written (no examples)
- Exams and solutions
Course Description
This course addresses the scientific basis for the development of new drugs. The first half of the semester begins with an overview of the drug discovery process, followed by fundamental principles of pharmacokinetics, pharmacodynamics, metabolism, and the mechanisms by which drugs cause therapeutic and toxic responses. The second half of the semester applies those principles to case studies and literature discussions of current problems with specific drugs, drug classes, and therapeutic targets.